A fly is a type of insect that inhabits Earth. In the Rabbids franchise, flies are portrayed as a typical distraction for the Rabbids, most notably in Rabbids Invasion episodes like "Until Rabbids Do You Part", "Rabbids Against the Machine" and "Holy Rabbid-Cow!". They are attracted to decay, trash, and moldy donuts.

In Mad Fly Rabbid, Professor Mad Rabbid accidentally turns himself into a Fly-Rabbid hybrid creature after he and a fly end up inside the Professor's gene-splicer.